Search on:
KI-1 ANTIGENS
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Antigens, CD30
Descriptor
Spanish
:
Antígenos CD30
Descriptor
Portuguese
:
Antígenos CD30
Synonyms
English
:
Antigens, Ki-1
Ber-H2 Antigens
CD30 Antigens
Ki-1 Antigens
Tumor Necrosis Factor Receptor Superfamily, Member 8
Tree Number:
D12.776.543.750.705.852.760.072
D23.050.285.025
D23.050.301.264.035.130
D23.101.100.110.130
D23.101.840.055
Definition
English
:
A member of the tumor
necrosis
factor receptor superfamily that may play a
role
in the regulation of
NF-KAPPA B
and
APOPTOSIS
. They are found on activated
T-LYMPHOCYTES
;
B-LYMPHOCYTES
;
NEUTROPHILS
;
EOSINOPHILS
;
MAST CELLS
and NK
CELLS
. Overexpression of CD30 antigen in hematopoietic malignancies make the antigen clinically useful as a biological tumor marker. Signaling of the receptor occurs through its
association
with TNF RECEPTOR-ASSOCIATED FACTORS.
History Note
English
:
94; CD30 ANTIGENS was CD30 ANTIGEN (NM) 1983-93
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
31645
Unique Identifier:
D017730
Occurrence in VHL
:
Similar:
DeCS
SciELO
LILACS
LIS